MY INTEREST

''If one has failed to develop curiosity and interest in the early years, it is a good idea to acquire them now, before it is too late to improve the quality of life''
― Mihaly Csikszentmihalyi

Day by day my interest in Pharmacology grows bigger, thou am just a beginner in the field but I believe am going somewhere!

If you have suggestions, any idea on newer areas in pharmacology that you would like to see, feel free to mention them in a comment.

These are the areas that would be touched:

*INTRODUCTORY PHARMACOLOGY

• Introduction to Pharmacology Including General Principles of Pharmacology
• Sources of drugs, Nomenclature and classification
• Terms and Definitions: Receptors, Dose-Response relationship theories of drug action, Agonists/Antagonists, LD50/ED50. Margin of safety, Toxicity, Side effects, Idiosyncracy, Tolerance, Tachyphylaxis, Resistance, Allergy, Teratogenicity.

Practicals: 

• Drug dilution
•  Dose-Response Curve (GPI)
• Agonist Antagonists
• LD50/ED50 determination
• PA2/PD2 determination
• Isolation of tissues.

*AUTONOMIC NERVOUS SYSTEM (ANS) PHARMACOLOGY

• Introduction to Nervous System
• Neurotransmitters, Neurotransmission in the ANS
• Division of ANS
• Cholinergic, Adrenergic, Somatic division and their Receptors
• Drugs acting on the cholinergic, Adrenergic and Somatic systems
• ANS receptor blockers
• Mechanism of Action of Autonomic drugs

Practicals:

• Agonists/ Antagonists (Cont’d)
• Anticholinestrases hydrolysis of Acetylcholine
• Identification of the unknown drugs

*SYSTEMIC PHARMACOLOGY (RESPIRATORY)

• Introduction of the Respiratory Tract
• Drugs used in Upper respiratory disorders: Nasal Decongestants
• Mucolytics, Expectorants and Antitussives
• Asthma and Therapy
• Chronic Obstructive Pulmonary Disease (COPD)

Practicals: 

• Drug kinetics I and II

*SYSTEMIC PHARMACOLOGY (GIT)

• Introduction to the GIT
• Common diseases of the GIT
• Gastrointestinal drugs: Drugs for treatment of ulcers, Emetics and Antiemetics, Purgatives and Laxatives, Anitdiarrhoeal, Appetite suppressanrts,stimulants

Practical: 

• GIT motility tests

*SYSTEMIC PHARMACOLOGY (CVS AND HAEMATINICS)

• Introduction to CVS
• Drugs used in the Management of CVS disorders
• Cardiac glycosides, Antihypertensives, Antiarrythmics, Antianginal, Diuretics,
• Renin-Angiotensin System
• Vasoactive peptides, Shock, Hypocholesterolemics
• Coagulants, Anticoagulants and Fibrinolytics
• Haematinics and Vitamins
• Anaemia

Practicals: 

• Drug and Exercise
• Anaesthesia and Respiration

*SYSTEMIC PHARMACOLOGY (ENDOCRINE)

• Introduction to Endocrine System
• Hormones and their classification
• Thyroid, Parathyroid, Pituitary, Adrenocortical, Estrogen, Progesterone, Androgen and anabolic steroids
• Insulin and Oral hypoglycemics
• Calcitonin and Vitamin D

Practicals:

• Drugs and rabbit intestine 
• Phrenic nerve-Diaphragm (PND) preparation
• Rat uterus preparation

*IMMUNOPHARMACOLOGY

•  Non-steroidal Anti-inflammatory drugs (NSAIDs)
• Pharmacology of Allergy
• Antagonists of Histamine
• Gout and Drugs
• Antirheumatoid drugs
• Immunosuppressant drugs

Practicals:

• Anti-inflammatory activity of drugs in laboratory animals
• Effect of histamine and anti-histamines on smooth muscle preparation 

*BIOCHEMICAL PHARMACOLOGY

• Principles of Biochemical Pharmacology
• Screening of various drugs: Analgesics, Sedatives, Hypnotics, Diuretics, Anaesthetics
• Drug Resistance
• Severe Adverse Reaction (SAR) of some group of drugs
• Transport of Drugs in biological system

Practicals: 

• Enzyme induction and inhibition 
• Absorption and Excretion of Sulphonamides/Aspirin

*TOXICOLOGY AND SOCIAL PHARMACOLOGY

• Principles of Toxicology
• Poisoning and its Management
• Herbicides, fungicides, rodenticides poisoning etc
• Poisoning by solvents, gases etc
• Food toxicology
• Toxins from animals
• Bacterial toxins
• Vaccines and Sera
• Disinfectants, Antiseptics, Ectoparasiticides
• Cosmetics, Radiation and Heavy metal poisoning/Chelating agents
• Drug abuse and Misuse, drug dependence
• Hallucinogens
• Alcoholism

Practicals: 

• Enzyme induction/inhibition
• Abserptin and Excretion of Sulphonal
• Toxicity studies 

*CHEMOTHERAPY

• Introduction to Chemotherapy
• Antimicrobials: Sulphonamides, Penicillins, Cephalosporins, Macrolides, Chloramphenicol, Tetracycline, Aminoglycosides
• Antituberculosis
• Antiparasitics: Introduction to parasitic diseases, Antihelminthes, Antiprotozoals, Antimalarials, Antifungals 
• Anticancers

Practicals: 

• Assay techniques
• Saline cathartics
• Rat fundus, Rectus abdominus and Vas deferens preparations

*CNS PHARMACOLOGY

• Introduction to CNS; Some physiological aspect of CNS (Sense organs and the cranial nerves)
• CNS neurotransmitters
• Anaesthetic agents (General and local)
• Barbiturates
• Anxiolytics
• Narcotic Analgesics
• Anticonvulsants
• Antidepressants
• Neuroleptics
• Ethanol
• CNS Stimulants

Practicals: 

• Anticonvulsant activity
• Antidepressant activity 
• Effects of Ethanol on CNS 
• Analgesic activity
• Sedative tests 

*ANIMAL MANAGEMENT

• Animal Cages and Design for different colonies of Laboratory Animals
• Animal House Services: Light, Heat, Temperature regulator, Ventilation, Water and Food intake, Drainage, Beddings
• Breeding
• Handling of Laboratory animals and Collection of blood, urine, faeces etc
• Routes of drug administration
• Euthanasia
• Laws involving the use of Laboratory animals
• Physiology of Laboratory Animals
• Diseases and Control of Laboratory Animal infections
• Drugs Used in Management/control of Laboratory Animal Diseases
• Method of Sterilisation
• Safety in Laboratory Animal House

Practicals: 

• Drug and Urine Input

I actually have a calendar where I have all the topics spaced out, with a little bit been shared every day.....yeah, let's see if this man can keep that going.